N-[2-(3,4-dimethoxyphenyl)ethyl]-N'-(2-methoxyphenyl)ethanediamide
AlkaPlorer ID: AK511826
Synonym: None
IUPAC Name: N-[2-(3,4-dimethoxyphenyl)ethyl]-N'-(2-methoxyphenyl)oxamide
Structure
SMILES: COC1=CC=CC=C1NC(=O)C(=O)NCCC1=CC=C(OC)C(OC)=C1
InChI: InChI=1S/C19H22N2O5/c1-24-15-7-5-4-6-14(15)21-19(23)18(22)20-11-10-13-8-9-16(25-2)17(12-13)26-3/h4-9,12H,10-11H2,1-3H3,(H,20,22)(H,21,23)
InChIKey: RJOWLZOMAQFOEE-UHFFFAOYSA-N
Reference
PubChem CID: 2248131
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 358.3940000000001
TPSA？: 85.89
MolLogP？: 2.0098
Number of H-Donors: 2
Number of H-Acceptors: 5
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Huh-7 | CC50 | 100000.0 | nM | 10.1073/pnas.0802982105 |
| Plasmodium falciparum | Plasmodium falciparum | EC50 | 10310.0 | nM | 10.1073/pnas.0802982105 |
| Plasmodium falciparum | Plasmodium falciparum | EC50 | 10780.0 | nM | 10.1073/pnas.0802982105 |
| Plasmodium yoelii | Plasmodium yoelii | Activity | nan | None | 10.1126/science.1211936 |
| None | Unchecked | IFI | 0.0 | % | 10.1073/pnas.0802982105 |