Pyridovericin
AlkaPlorer ID: AK518727
Synonym: None
IUPAC Name: 4-hydroxy-3-[(2E,4E)-6-(hydroxymethyl)-4-methylocta-2,4-dienoyl]-5-(4-hydroxyphenyl)-1H-pyridin-2-one
Structure
SMILES: CCC(/C=C(C)/C=C/C(=O)C1=C(O)N=CC(C2=CC=C(O)C=C2)=C1O)CO
InChI: InChI=1S/C21H23NO5/c1-3-14(12-23)10-13(2)4-9-18(25)19-20(26)17(11-22-21(19)27)15-5-7-16(24)8-6-15/h4-11,14,23-24H,3,12H2,1-2H3,(H2,22,26,27)/b9-4+,13-10+
InChIKey: RZNMCGWGYUMEOL-HTKXOECOSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Beauveria bassiana | Beauveria | Cordycipitaceae | Hypocreales | Sordariomycetes | Ascomycota | Fungi | Eukaryota |
Properties Information
Molecule Weight: 369.4170000000001
TPSA？: 110.88
MolLogP？: 3.569100000000002
Number of H-Donors: 4
Number of H-Acceptors: 6
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Anandamide amidohydrolase | Inhibition | nan | % | 10.1016/j.bmc.2017.02.031 |
| Homo sapiens | Cannabinoid CB1 receptor | Inhibition | 20.0 | % | 10.1016/j.bmc.2017.02.031 |
| Homo sapiens | Cannabinoid CB2 receptor | Inhibition | 20.0 | % | 10.1016/j.bmc.2017.02.031 |
| Mus musculus | Monoacylglycerol lipase ABHD12 | Inhibition | nan | % | 10.1016/j.bmc.2017.02.031 |
| Mus musculus | Monoacylglycerol lipase ABHD6 | Inhibition | nan | % | 10.1016/j.bmc.2017.02.031 |
| None | Unchecked | Inhibition | nan | % | 10.1016/j.bmc.2017.02.031 |