Fuligopyrone
AlkaPlorer ID: AK556361
Synonym: None
IUPAC Name: (2E,4E)-N-[2-(4-hydroxy-6-oxopyran-2-yl)ethyl]-5-(4-hydroxyphenyl)penta-2,4-dienamide
Structure
SMILES: O=C1C=C(O)C=C(CCN=C(O)/C=C/C=C/C2=CC=C(O)C=C2)O1
InChI: InChI=1S/C18H17NO5/c20-14-7-5-13(6-8-14)3-1-2-4-17(22)19-10-9-16-11-15(21)12-18(23)24-16/h1-8,11-12,20-21H,9-10H2,(H,19,22)/b3-1+,4-2+
InChIKey: WDDXZETYSGHOSC-ZPUQHVIOSA-N
Reference
Slime moulds (Myxomycetes) as a source of new biologically active metabolites
PubChem CID: 139584111
LOTUS: LTS0000964
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| None | None | Physaraceae | Physariida | Eumycetozoa | Evosea | None | Eukaryota |
Properties Information
Molecule Weight: 327.33600000000007
TPSA？: 103.26
MolLogP？: 2.819600000000001
Number of H-Donors: 3
Number of H-Acceptors: 5
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Bacillus subtilis | Bacillus subtilis | MIC | 100.0 | ug.mL-1 | 10.1021/acs.jnatprod.2c00989 |
| Candida albicans | Candida albicans | MIC | 200.0 | ug.mL-1 | 10.1021/acs.jnatprod.2c00989 |
| Eragrostis cilianensis | Eragrostis cilianensis | MIC | 100.0 | ug.mL-1 | 10.1021/acs.jnatprod.2c00989 |
| Saccharomyces cerevisiae | Saccharomyces cerevisiae | MIC | 200.0 | ug.mL-1 | 10.1021/acs.jnatprod.2c00989 |
| Staphylococcus aureus | Staphylococcus aureus | MIC | 100.0 | ug.mL-1 | 10.1021/acs.jnatprod.2c00989 |
| Tritrichomonas foetus | Tritrichomonas foetus | LD99 | 100.0 | ug ml-1 | 10.1021/acs.jnatprod.2c00989 |
| None | Unchecked | IC50 | 200000.0 | nM | 10.1021/acs.jnatprod.2c00989 |