None
AlkaPlorer ID: AK581528
Synonym: None
IUPAC Name: 2,10,11-trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-3-one
Structure
SMILES: COC1=CC2=C3C=C4C=C(OC)C(OC)=CC4=CN3CCC2=CC1=O
InChI: InChI=1S/C20H19NO4/c1-23-18-10-15-12(7-17(18)22)4-5-21-11-14-9-20(25-3)19(24-2)8-13(14)6-16(15)21/h6-11H,4-5H2,1-3H3
InChIKey: YKOWIGFWFQCIKO-UHFFFAOYSA-N
Reference
Studies on Indonesian Medicinal Plants VI* Further Alkaloids from Fibraurea chloroleuca
PubChem CID: 10246448
LOTUS: LTS0166909
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|---|---|---|---|---|---|---|
| Penianthus zenkeri | Penianthus | Menispermaceae | Ranunculales | Magnoliopsida | Streptophyta | Viridiplantae | Eukaryota |
Properties Information
Molecule Weight: 337.3750000000001
TPSA？: 48.0
MolLogP？: 1.2351
Number of H-Donors: 0
Number of H-Acceptors: 5
RingCount: 4
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | KB | IC50 | 29000.0 | nM | 10.1021/np8004437 |
| Homo sapiens | MCF7 | Activity | nan | None | 10.1021/np060285e |
| Homo sapiens | MCF7 | IC50 | 7000.0 | nM | 10.1021/np060285e |
| Homo sapiens | MCF7 | IC50 | 25000.0 | nM | 10.1021/np060285e |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 900.0 | nM | 10.1021/np8004437 |