3,5-dinitro-N-(pyridin-2-yl)benzamide
AlkaPlorer ID: AK581859
Synonym: None
IUPAC Name: 3,5-dinitro-N-pyridin-2-ylbenzamide
Structure
SMILES: O=C(NC1=CC=CC=N1)C1=CC([N+](=O)[O-])=CC([N+](=O)[O-])=C1
InChI: InChI=1S/C12H8N4O5/c17-12(14-11-3-1-2-4-13-11)8-5-9(15(18)19)7-10(6-8)16(20)21/h1-7H,(H,13,14,17)
InChIKey: YLGDFLHPLMWCJJ-UHFFFAOYSA-N
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 288.219
TPSA？: 128.27
MolLogP？: 2.1503
Number of H-Donors: 1
Number of H-Acceptors: 6
RingCount: 2
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Plasmodium falciparum | Hemozoin | IC50 | 134000.0 | nM | 10.1021/acs.jmedchem.6b00719 |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 22000.0 | nM | 10.1021/acs.jmedchem.6b00719 |
| Plasmodium falciparum | Plasmodium falciparum | IC50 | 24000.0 | nM | 10.1021/acs.jmedchem.6b00719 |