N-(4-methoxyphenyl)-3-[(phenylcarbonyl)amino]benzamide
AlkaPlorer ID: AK597374
Synonym: None
IUPAC Name: 3-benzamido-N-(4-methoxyphenyl)benzamide
Structure
SMILES: COC1=CC=C(NC(=O)C2=CC=CC(NC(=O)C3=CC=CC=C3)=C2)C=C1
InChI: InChI=1S/C21H18N2O3/c1-26-19-12-10-17(11-13-19)22-21(25)16-8-5-9-18(14-16)23-20(24)15-6-3-2-4-7-15/h2-14H,1H3,(H,22,25)(H,23,24)
InChIKey: ZVRUHBVLQNTQTR-UHFFFAOYSA-N
Reference
PubChem CID: 2186725
Source
| Species | Genus | Family | Order | Class | Phylum | Kingdom | Domain |
|---|
Properties Information
Molecule Weight: 346.386
TPSA？: 67.43
MolLogP？: 4.199800000000002
Number of H-Donors: 2
Number of H-Acceptors: 3
RingCount: 3
Activities Information
| Organism | Target Name | Standard Type | Standard Value | Standard Units | doi |
|---|---|---|---|---|---|
| Homo sapiens | Breast cancer type 1 susceptibility protein | Potency | 1122.0 | nM | None |
| Homo sapiens | Guanine nucleotide-binding protein G(s), subunit alpha | Potency | 22387.2 | nM | None |
| Homo sapiens | Histone-lysine N-methyltransferase MLL | Potency | 39810.7 | nM | None |
| Homo sapiens | Importin subunit beta-1/Snurportin-1 | Potency | 125892.5 | nM | None |
| Homo sapiens | Niemann-Pick C1 protein | Potency | 6309.6 | nM | None |
| Homo sapiens | Potassium channel subfamily K member 3 | Inhibition | 10.0 | % | 10.1021/acs.jmedchem.1c00378 |
| Homo sapiens | Rap guanine nucleotide exchange factor 3 | Potency | 17782.8 | nM | None |
| Homo sapiens | Ras-related protein Rab-9A | Potency | 6309.6 | nM | None |
| Homo sapiens | Tyrosyl-DNA phosphodiesterase 1 | Potency | 18356.4 | nM | None |
| Mus musculus | Nuclear receptor ROR-gamma | Potency | 6309.6 | nM | None |
| Photinus pyralis | Luciferin 4-monooxygenase | Potency | 8492.1 | nM | None |
| None | Unchecked | Potency | 3981.1 | nM | None |
| None | Unchecked | Potency | 15848.9 | nM | None |
| None | Unchecked | Potency | 22387.2 | nM | None |
| None | Unchecked | Potency | 39810.7 | nM | None |