N′-Methylniphimycin, a novel minor congener of niphimycin fromStreptomyces spec. 57-13

Journal of Basic Microbiology
1998.0

Abstract

A novel natural niphimycin analog, N′-methylniphimycin was isolated from the culture broth of the Streptomyces spec. 57-13. The chemical constitution was elucidated from the physico-chemical properties, NMR techniques and mass spectrometry to be a 36-membered macrolide related to azalomycin F5a, shurimycin B and RS-22C. N′-methylniphimycin displayed moderate activity against some yeasts and filamentous fungi.

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