A simple and efficient stereoselective total synthesis of (−)-sedridine

International Journal of Chemical and Analytical Science
2013.0

Abstract

An asymmetric synthesis of the piperidine alkaloid ()-sedridine isolated from Sedum acre, has been accomplished starting from S-malic acid as the chiral precursor employing Maruoka Keck allylation, azide nucleophillic substitution and ring closing metathesis as the key steps.

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