Two new acridone alkaloids, l-hydroxy-3,4-dimethoxy- 10-methylacridan-9-one (11) and l-hydroxy-3-geranyloxy-4-methoxy-10-methylacridan-9-one (12), have been isolated from Sarcomelicope lezocarpa wood and bark. Their structures have been elucidated by spectral analysis and confirmed by chemical correlation for compound 11, and by X-ray diffraction analysis for compound 12. In addition, eight other acridones (3-10) and two furo{2,3b] quinolines (1,2) have been isolated from the leaves, wood, and bark of the same species.