Thiazohalostatin, a new cytoprotective substance produced by Actinomadura. I. Taxonomy, production, isolation and biological activities.

The Journal of Antibiotics
1993.0

Abstract

Thiazohalostatin has been isolated from the culture broth of Actinomadura sp. by a screening program designed to find novel cytoprotective substances. It was purified by use of column chromatography on silica gel, reversed phase HPLC and then isolated as colorless powder. Thiazohalostatin prevented cell death caused by calcium overload and exhibited an inhibitory activity against lipid peroxidation.

Knowledge Graph

Similar Paper

Thiazohalostatin, a new cytoprotective substance produced by Actinomadura. I. Taxonomy, production, isolation and biological activities.
The Journal of Antibiotics 1993.0
Thiazohalostatin, a new cytoprotective substance produced by Actinomadura. II. Physico-chemical properties and structure determination.
The Journal of Antibiotics 1993.0
Thiazostatin A and thiazostatin B. new antioxidants produced by Streptomyces tolurosus.
The Journal of Antibiotics 1989.0
Rumbrin, a new cytoprotective substance produced by Auxarthron umbrinum. I. Taxonomy, production, isolation and biological activities.
The Journal of Antibiotics 1993.0
New Diphenazines with Neuronal Cell Protecting Activity, Phenazostatins A and B, Produced by Streptomyces sp.
The Journal of Antibiotics 1997.0
Thiasporines A–C, Thiazine and Thiazole Derivatives from a Marine-Derived <i>Actinomycetospora chlora</i>
Journal of Natural Products 2015.0
A Neuronal Cell Protecting Substance, 4-Demethoxymichigazone, Produced by Streptomyces halstedii.
The Journal of Antibiotics 1996.0
Studies on free radical scavenging substances from microorganisms. I. Carazostatin, a new free radical scavenger produced by Streptomyces chromofuscus DC 118.
The Journal of Antibiotics 1989.0
Thiasporines A–C, Thiazine and Thiazole Derivatives from a Marine-Derived Actinomycetospora chlora
Journal of Natural Products 2015.0
Cyclothiazomycin, a novel polythiazole-containing peptide with renin inhibitory activity. Taxonomy, fermentation, isolation and physico-chemical characterization.
The Journal of Antibiotics 1991.0