Axinellamines A and B, New Pyrrole Alkaloids of the Marine Sponge Axinella Sp.

HETEROCYCLES
1998.0

Abstract

Two new pyrrole alkaloids, axinellamines A and B, were isolated from the Caribbean marine sponge Axinella sp. and their structures were established on the basis of spectroscopic data, including 2D NMR spectroscopy. Axinellamine A was determined to be 2-((E, E)-6-methyl-2,4-octadieny1)pyrrole while axinellamine B was a dimer of axinellamine A, hut containing an additional Me,C unit between the C-5 and C-5' carbons of the two pyrrole rings.

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