Evaluation of Constituents of Piper retrofractum Fruits on Neurotrophic Activity

Journal of Natural Products
2013.0

Abstract

Three new compounds, 1-3, together with 22 known compounds, were isolated from the fruits of Piper retrofractum. The structures of the new compounds were elucidated on the basis of spectroscopic data analysis and comparison with literature values. Compound 1 was found to enhance the neurite outgrowth of NGF-mediated PC12 cells at concentrations ranging from 0.1 to 10 μM.

DOI： 10.1021/np300911b

Knowledge Graph

Similar Paper

Evaluation of Constituents of <i>Piper retrofractum</i> Fruits on Neurotrophic Activity
Journal of Natural Products 2013.0
Piperidine alkaloids from Piper retrofractum fruits
Phytochemistry 1992.0
A new phenylpropanoid and an alkylglycoside from Piper retrofractum leaves with their antioxidant and α-glucosidase inhibitory activity
Bioorganic &amp; Medicinal Chemistry Letters 2014.0
Spirocyclic Nortriterpenoids with NGF-Potentiating Activity from the Fruits of <i>Leonurus heterophyllus</i>
Journal of Natural Products 2012.0
Larvicidal Activity of Isobutylamides Identified in <i>Piper nigrum</i> Fruits against Three Mosquito Species
Journal of Agricultural and Food Chemistry 2002.0
Larvicidal Activity of Isobutylamides Identified in Piper nigrum Fruits against Three Mosquito Species
Journal of Agricultural and Food Chemistry 2002.0
Effects of amide constituents from pepper on adipogenesis in 3T3-L1 cells
Bioorganic &amp; Medicinal Chemistry Letters 2008.0
LC-MS Analysis and Structural Determination of New Amides from Javanese Long Pepper (<i>Piper retrofractum</i>)
Bioscience, Biotechnology, and Biochemistry 1993.0
Polyphenols and alkaloids from piper species
Phytochemistry 1998.0
Novel NGF-potentiating diterpenoids from a Brazilian medicinal plant, Ptychopetalum olacoides
Bioorganic &amp; Medicinal Chemistry Letters 2009.0