Literature

Abstract

Seven sesterterpene sulfates (1-7) were isolated from the tropical sponge Dysidea sp. and their inhibitory activities against isocitrate lyase (ICL) from Candida albicans were evaluated. Among the isolated natural products compound 6 and 7 were found to be strong ICL inhibitors. The isolated compounds (1-7) also showed potent antibacterial effect against Bacillus subtilis and Proteus vulgaris, but did not display antifungal activity.

DOI： 10.1016/j.bmcl.2008.09.059

Inhibition of Candida albicans isocitrate lyase activity by sesterterpene sulfates from the tropical sponge Dysidea sp.

Bioorganic & Medicinal Chemistry Letters 2008.0

5-Hydroxyindole-type alkaloids, as Candida albicans isocitrate lyase inhibitors, from the tropical sponge Hyrtios sp.

Bioorganic & Medicinal Chemistry Letters 2009.0

Indole Alkaloids from Tropical Sponge Hyrtios sp. as Isocitrate Lyase Inhibitors

Natural Product Communications 2018.0

Inhibition of Candida albicans isocitrate lyase activity by cadiolides and synoilides from the ascidian Synoicum sp.

Bioorganic & Medicinal Chemistry Letters 2013.0

Bioactive Sulfated Sesterterpene Alkaloids and Sesterterpene Sulfates from the Marine Sponge Fasciospongia sp.

Journal of Natural Products 2009.0

Bioactive Sulfated Sesterterpene Alkaloids and Sesterterpene Sulfates from the Marine Sponge Fasciospongia sp.