Structures of topostins, DNA topoisomerase I inhibitors of bacterial origin

Structures of topostins, DNA topoisomerase I inhibitors of bacterial origin Topostatin, a Novel Inhibitor of Topoisomerases I and II Produced by Thermomonospora alba Strain No. 1520. I. Taxonomy, Fermentation, Isolation and Biological Activities. Topostatin, a Novel Inhibitor of Topoisomerases I and II Produced by Thermomonospora alba Strain No. 1520. III. Inhibitory Properties. Novel Human Topoisomerase I Inhibitors, Topopyrones A, B, C and D. I. Producing Strain, Fermentation, Isolation, Physico-chemical Properties and Biological Activity. Isoaurostatin, a Novel Topoisomerase Inhibitor Produced by <i>Thermomonospora </i><i>a</i><i>lba</i> Novel ceramide 1-sulfates, potent DNA topoisomerase I inhibitors isolated from the Bryozoa Watersipora cucullata Synthesis and anti-staphylococcal activity of novel bacterial topoisomerase inhibitors with a 5-amino-1,3-dioxane linker moiety A new topoisomerase-II inhibitor, BE-10988, produced by a streptomycete. I. Taxonomy, fermentation, isolation and characterization. A new topoisomerase-II inhibitor, BE-10988, produced by a streptomycete. I. Taxonomy, fermentation, isolation and characterization. Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from an actinomycete