Callus tissue from the stems of Phellodendron amurense (Rutaceae) produced the indolopyridoquinazoline type alkaloids, rutaecarpine, 7,8-dehydrorutaecarpine, which is new from a natural source, canthin-6-one, and three furoquinoline alkaloids, dictamnine, gamma-fagarine and skimmianine, as the main alkaloid components, along with a small amount of three isoquinoline alkaloids (berberine, palmatine and magnoflorine).The indolopyridoquinazoline and furoquinoline type alkaloids are isolated for the first time from Phellodendron amurense. (C) 1998 Elsevier Science Ltd. All rights reserved.