<p>Three new quinazoline derivatives (<bold>1–3</bold>), one new oxepin-containing natural product (<bold>4</bold>) and four new cyclopenin derivatives (<bold>5–7</bold> and <bold>9</bold>) have been isolated from an EtOAc extract of the Taiwan Kueishantao hydrothermal vent crab-associated fungus <italic>Aspergillus versicolor</italic> XZ-4.</p>