The flavonoid glycosides of Euphorbia retusa and E. sanctae-catharinae are reported. Besides a number of common flavonol glycosides, kaempferol and quercetin 3-glucuronide-7-glucosides are reported for the first time.Euphorbia is represented in Egypt by some 35 species [l]. A number of these species have been studied previously, thus quercetin 3-rhamnoside has been isolated from Euphorbia hypericifolia [2] and E. geniculata [3]. Quercetin 3-galactoside and 3-arabinoside were identified in E. prostrata [4], while rhamnetin 3-galactoside was detected in E. hypericifolia [2] and E. prostrata [3]. E. grandifolia proved to contain apigenin 7-glucoside [5], which was also found in E. prostrata [3]. Four other Euphorbia species have also been investigated. Thus from E. esula kaempferol 3-glucuronide was isolated [6] and quercetin 3-galactoside-2"-gallate was identified in both E. verrucosa [7] and E. sequieriana [8], while its isomer quercetin 3-galactoside-6"-gallate was detected in E. platiphyllos [7]. In the present report, two more Euphorbia species were investigated, namely E. retusa Forssk. (= E. kuhirensis Raeusch.) and E. sanctae-catharinae A. Fayed. The latter is a newly reported species [9]. Both plants proved to contain kaempferol and quercetin glycosides with their 3 glucuronides forming the major glycosides in E. retusa and quercetin 3-rhamnoside forming the major glycoside in E. sanctae-catharinae. The results are outlined in Table 1. Kaempferol and quercetin 3-glucuronide-7-glucosides are reported here for the first time.