Overexpression of phosphopantetheinyl transferase (PPtase)-encoding genes <i>sfp</i> and <i>svp</i> in the marine-derived <i>Verrucosispora</i> sp. SCSIO 40062 led to the production of two new aminofuran monomers, proximicin F (<b>1</b>) and proximicin G (<b>3</b>) and a new dimer diproximicin A (<b>2</b>), along with two known compounds, proximicins B (<b>4</b>) and C (<b>5</b>). Their structures were unambiguously elucidated on the basis of detailed NMR spectroscopic analysis and high-resolution electrospray ionization mass spectrometry (HRESIMS) data. Proximicin B (<b>4</b>) showed moderate antibacterial activities against <i>Staphylococcus aureus</i>, methicillin-resistant <i>S. aureus</i>, and <i>Bacillus subtilis</i>.