Isolation and Structure Elucidation of Chlorofusin, a Novel p53-MDM2 Antagonist from a Fusarium sp.

Isolation and Structure Elucidation of Chlorofusin, a Novel p53-MDM2 Antagonist from a <i>Fusarium</i> sp. Potent and Orally Active Small-Molecule Inhibitors of the MDM2−p53 Interaction Discovery, Synthesis, and Biological Evaluation of Orally Active Pyrrolidone Derivatives as Novel Inhibitors of p53–MDM2 Protein–Protein Interaction Discovery of new pyridoacridine alkaloids from Lissoclinum cf. badium that inhibit the ubiquitin ligase activity of Hdm2 and stabilize p53 The development of piperidinones as potent MDM2-P53 protein-protein interaction inhibitors for cancer therapy Fungerin, a New Antifungal Alkaloid fromFusariumsp. Small Molecules Simultaneously Inhibiting p53-Murine Double Minute 2 (MDM2) Interaction and Histone Deacetylases (HDACs): Discovery of Novel Multitargeting Antitumor Agents Discovery of Novel 3,3-Disubstituted Piperidines as Orally Bioavailable, Potent, and Efficacious HDM2-p53 Inhibitors Hoiamide D, a marine cyanobacteria-derived inhibitor of p53/MDM2 interaction Using Jasplakinolide to Turn on Pathways that Enable the Isolation of New Chaetoglobosins from <i>Phomospis asparagi</i>