Diheteropeptin, a Novel Substance with TGF-.BETA.-like Activity, Produced by a Fungus, Diheterospora chlamydosporia. II. Physico-chemical Properties and Structure Elucidation.

The Journal of Antibiotics
2000.0

Abstract

The structure of diheteropeptin (1), a TGF-beta-like active substance from Diheterospora chlamydosporia Q58044, was determined to be a new cyclotetrapeptide, cyclo[2aminoisobutyryl-(S)-phenylalanyl-(R)-prolyl-(2S,8R,9R)-2-am ino-8,9-dihydroxydecanoyl-] by NMR, mass spectrometric and chemical studies.

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