Tortifoline, a novel (20S, 22R)-5.ALPHA.-cevanine alkaloid from Fritillaria tortifolia.

Chemical and Pharmaceutical Bulletin
1989.0

Abstract

A new D/E cis (20S,22R,25S)-20-deoxy-5a-cevanine alkaloid, tortifoline (1), was isolated from the Chinese herbal drug, "takuri baimo" (dried bulbs of Fritillaria tortifolia). The structure of 1 was deduced from spectral data and its absolute configuration was confirmed by X-ray crystallographic analysis.

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