Isolation and structure of the symmetrical disteroidal alkaloids cephalostatin 12 and cephalostatin 13

Bioorganic & Medicinal Chemistry Letters
1994.0

Abstract

Re-examination of a Western Indian Ocean worm Cephalodiscus gilchristi has led to discovery of cephalostatins 12 and 13. Cephalostatin 12 (2) proved to be the first example of a symmetrical disteroidal alkaloid. Both new cephalostatins significantly inhibited growth of animal and human cancer cell lines. © 1994.

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