Fourteen alkaloids were isolated from the trunk of Melodinus suaveolens. Thirteen of them were identified as Δ14-vincine, vindolinine, 11-methoxytabersonine, vincadifformine, hazuntine, 11-hydroxytabersonine, 11-methoxyvineadifformine, cathovalinine, vincoline, 19R-hydroxytabersonine, 11-methoxy-19R-hydroxytabersonine, 11,19R-dihydroxytabersonine and tabersonine. The last one is a new alkaloid, named suaveolenine; its structural elucidation was achieved by means of detailed spectral analysis. © 1991.