Colubricidin A, a novel macrolide antibiotic from a Streptomyces sp.

Tetrahedron Letters
1999.0

Abstract

A new 34-membered macrolide antibiotic, colubricidin A (1), was isolated from the fermentation broth of a new streptomyces species. Its structure was elucidated on the basis of analysis of the spectroscopic data and chemical degradation. It was identified as a glycomacrolide with an unprecedented aromatic chromophore. Colubricidin A showed excellent activity against Gram-positive bacteria.

DOI： 10.1016/S0040-4039(99)01968-1

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