A new marine pyrazine congener, clavulazine (21, was obtained from the polar portion of the MeOH extract of the Okinawan soft coral Chvuhria viridis as its acetate (1). The shucture of 2 was determined on the basis of spectral analysis and chemical conversion. The absolute configuration of 2 was unambigously determined by X-Ray crystallographic analysis on the pbromobenzoate (3). The Okinawan soft coral, Chvularh viridir Quoy and Gaimard (class Anthozoa, subclass Octocorallia, order Stolonifera), contains numerous structurally unique antitumor prostanoids' and cytotoxic steroid^.^ In recent study on C. viridis, new prostanoid lac tone^,^ prostanoid carboxylate salts4 and steroids5 were isolated. To find bioactive compounds in the polar portion of the MeOH extract of viridis, a new pyrazine congener, clavulazine (2), was obtained. This paper describes the isolation and structure determination of 2.