Phorbasterones A−D, Cytotoxic Nor-Ring A Steroids from the Sponge Phorbas amaranthus

Journal of Natural Products
2004.0

Abstract

The sponge Phorbas amaranthus from Florida contains the new ring A-contracted steroids, phorbasterones A-D, and the known anthosterones A and B. The structures of phorbasterones A-D were determined by interpretation of their spectroscopic data. Phorbasterones show moderate cytotoxicity against HCT-116 tumor cells.

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