Cyclic lipoundecapeptide lokisin from Pseudomonas sp. strain DSS41

Tetrahedron Letters
2002.0

Abstract

Lokisin was isolated from Pseudomonas sp. strain DSS41 as part of a study of prospective anti-fungal bio-control agents. Based on NMR and MS studies, lokisin was tentatively identified as pholipeptin. However, detailed analysis of the amino acid constituents by chiral gas chromatography revealed a different D-/L-leucine ratio of 3:2 and the allo-isomer of threonine. Lokisin represents a new structural variation in the cyclic lipoundecapeptide class. © 2002 Elsevier Science Ltd. All rights reserved.

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