<jats:title>Abstract</jats:title><jats:p>From chemical degradation experiments and spectroscopical data structure I is deduced for schizozygine, the major alkaloid of <jats:italic>Schizozygia caffaeoides</jats:italic> (B<jats:sc>OJ</jats:sc>.) B<jats:sc>AILL</jats:sc>. The given relative configuration is suggested by experiments indicating a strain‐free ring system.