The leaves and fruits of Mellaleuca cajuputi Powell are known to be rich in an essential oil used as a perfume and a popular remedy (Jamu medicine) for various ailments in Indonesia and Malaysia. In continuing research on bioactive compounds from medicinal plants to search for antimalarial and antibacterial active components, the title compound, 5-hydroxy-7-methoxy-2,6,8-trimethyl-4H-chromen-4-one (8-methyleugenitin, C13H14O4), was isolated from the leaves but showed no cytotoxicity, antibacterial or antimalarial activities. Its crystal structure is reported: the chromone unit is essentially planar, with methyl and hydroxyl groups lying in the benzene ring plane while the methoxy substituent is perpendicular. An intramolecular O—H---O hydrogen bond generates an S(6) ring motif. The crystal structure is stabilized by intramolecular O—H---O, weak C—H---O hydrogen bonds, together with C—H---π and π–π interactions, and molecules are arranged in an antiparallel fashion into columns along the [100] direction.