Vicenistatin, a novel 20-membered macrocyclic lactam antitumor antibiotic.

The Journal of Antibiotics
1993.0

Abstract

A new antitumor antibiotic vicenistatin was isolated from the culture broth of Streptomyces sp. HC34. The structure of vicenistatin was elucidated by NMR spectral analysis. Vicenistatin exhibited antitumor activity against human colon carcinoma Co-3 in the xenograft model.

Knowledge Graph

Similar Paper

Vicenistatin, a novel 20-membered macrocyclic lactam antitumor antibiotic.
The Journal of Antibiotics 1993.0
Isolation and Structure Elucidation of Vicenistatin M, and Importance of the Vicenisamine Aminosugar for Exerting Cytotoxicity of Vicenistatin.
The Journal of Antibiotics 2001.0
Characterization of the Aminosugar Biosynthetic and Regulatory Genes of Vicenistatin in Monodonata labio-Associated Streptomyces parvus SCSIO Mla-L010
Journal of Natural Products 2022.0
Studies on viridenomycin, a novel 24-membered macrocyclic polyene lactam antibiotic.
The Journal of Antibiotics 1992.0
Studies on a novel antitumor antibiotic, phenazinomycin: Taxonomy, fermentation, isolation, and physicochemical and biological characteristics.
The Journal of Antibiotics 1989.0
Himastatin, a new antitumor antibiotic from Streptomyces hygroscopicus. I. Taxonomy of producing organism, fermentation and biological activity.
The Journal of Antibiotics 1990.0
Isolation and structural elucidation of new 18-membered macrolide antibiotics, viranamycins A and B.
The Journal of Antibiotics 1991.0
RETRACTED: Sannastatin, a novel toxic macrolactam polyketide glycoside produced by actinomycete Streptomyces sannanensis
Bioorganic & Medicinal Chemistry Letters 2011.0
Himastatin, a New Antitumor Antibiotic from Streptomyces hygroscopicus. III. Structural Elucidation.
The Journal of Antibiotics 1996.0
Structures of Duocarmycins, novel antitumor antibiotics produced by Streptomyces sp.
Chemical and Pharmaceutical Bulletin 1988.0