Studies on new vasodilators, WS-1228 A and B. I. Discovery, taxonomy, isolation and characterization.

The Journal of Antibiotics
1982.0

Abstract

New vasodilators, designated WS-1228 A and B have been discovered in the culture filtrate of a strain of Streptomyces aureofaciens. The active compounds were purified by column chromatography with Diaion HP-20 and silica gel, and finally separated from each other by high performance liquid chromatography. They were obtained as pale yellow crystals and their molecular formulae were both C11H17N3O.

Knowledge Graph

Similar Paper

Studies on new vasodilators, WS-1228 A and B. I. Discovery, taxonomy, isolation and characterization.
The Journal of Antibiotics 1982.0
WS-7338, new endothelin receptor antagonists isolated from Streptomyces sp. No. 7338. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities.
The Journal of Antibiotics 1992.0
WS009 A and B, new endothelin receptor antagonists isolated from Streptomyces sp. No. 89009. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities.
The Journal of Antibiotics 1992.0
Amauromine, a new vasodilator Taxonomy, isolation and characterization.
The Journal of Antibiotics 1984.0
W S75624 A and B, New Endothelin Converting Enzyme Inhibitors Isolated from Saccharothrix sp. No. 75624. II. Structure Elucidation of W S75624 A and B.
The Journal of Antibiotics 1995.0
Triacsins, new inhibitors of acyl-CoA synthetase produced by Streptomyces sp.
The Journal of Antibiotics 1986.0
Studies on new antiplatelet agents, WS-30581 A and B.
The Journal of Antibiotics 1984.0
Amauromine, a new vasodilator Taxonomy, isolation and characterization.
The Journal of Antibiotics 1984.0
WS-9659 A and B, novel testosterone 5.ALPHA.-reductase inhibitors isolated from a Streptomyces. I. Taxonomy, fermentation, isolation, physico-chemical characteristics.
The Journal of Antibiotics 1989.0
WS009 A and B, new endothelin receptor antagonists isolated from Streptomyces sp. No. 89009. II. Biological characterization and pharmacological characterization of WS009 A and B.
The Journal of Antibiotics 1992.0