Tyrosine and hydantoin derivatives from the fungus Phoma herbarum PSU-H256 isolated from Hevea brasiliensi s

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2017.0

Abstract

Six new compounds including four tyrosine derivatives (1e4), and two hydantoin derivatives (5e6) were obtained from the investigation of the endophytic fungus Phoma herbarum PSU-H256, which was isolated from a leaf of Hevea brasiliensis. Their structures were determined by analysis of spectroscopic data, especially 1D and 2D NMR. The relative configurations were assigned using NOEDIFF data while the absolute configurations were established by comparison of the optical rotations and circular dichroism data with those of structurally related compounds.

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