Recently we reported the characterization and structure determination of the new, natural aporphines nandigerine, N-methylnandigerine, ovigerine, N-methylovigerine, and hernovine from Hernandia ovigera L.; in addition the known isocorydine and the dimeric base thalicarpine (I) were isolated. We now wish to describe the isolation of three additional compounds from this plant. They are laurotetanine, N-methyl-6,7-dimethoxyisoquinolone (II) and a new base, hernandaline (III). Compound (III) represents a new, elaborated aporphine structural type, whose structure was confirmed by spectral data (UV, IR, NMR, mass spectrometry) and synthesis from (+)-N-methyllaurotetanine and excess 6-methoxyveratraldehyde in the presence of copper in pyridine. In the course of a broad chemotaxonomic survey of the genus Hernandia, we have isolated and characterized eleven alkaloids from the bark of the Jamaican species, H. catalpifolia. These include bases also occurring in H. ovigera: isocorydine, hernovine, ovigerine, N-methylovigerine, N-methylnandigerine, and nandigerine (the major alkaloid), as well as norisocorydine, O,O-dimethyloorytuberine, I-methyllaurotetanine, laurolitsine and a new base, catalpifoline (V), whose structure was proven by identity with the diazomethane alkylation product of hernovine. Although there is considerable similarity in the alkaloidal constituents of the East Indian H. ovigera and the West Indian H. catalpifolia, the benzylisoquinoline-aporphine dimer thalicarpine and hernandaline (III) are absent in the West Indian species.