Pyloricidins, Novel Anti-Helicobacter pylori Antibiotics Produced by Bacillus sp. I. Taxonomy, Fermentation and Biological Activity.

The Journal of Antibiotics
2001.0

Abstract

Novel anti-Helicobacter pylori antibiotics, pyloricidins A, A1, A2, B, C and D, were discovered in the culture broth of two bacilli strains. Pyloricidins selectively inhibited the growth of H. pylori. Pyloricidin B was efficacious in the treatment of gastric infection caused by H. pylori in Mongolian gerbils and may be promising for cure of H. pylori infection as a single agent.

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