In addition to echinopsine and echinopsidine, a new alkaloid, echinozolinone, has been identified in Echinops echinatus as 3(2-hydroxyethyl)-4(3H)-quinazolinone from its spectral data. This is the first report of alkaloids from this plant and the first occurrence of a 4-quinazolinone alkaloid in the Compositae. © 1987.