The compounds isoknipholone, isoknipholone anthrone, foliosone and isofoliosone were isolated from the stem of Kniphofia foliosa and their structures determined by spectral analyses. In addition, the known compounds, aloesaponol III, aloesaponol III-8-methyl ether and 4,6-dihydroxy-2-methoxyacetophenone were isolated and identified.