Alkaloids of Galanthus elwesii

Phytochemistry
1995.0

Abstract

Six new lycorenine-type alkaloids, (+)-5-methoxy-9-0-demethylhomolycorine, (+)-galwesine, (+)-9-0-demethylgalwesine, (+)-16-hydroxygalwesine, (+)-16-hydroxy-9-0-demethylgalwesine and galasine, were isolated from whole plants of Galanthus elwesii. Additionally, 12 known alkaloids, (-)-galanthamine, (-)-sanguinine, (-)-leucotamine, (-)-0-methylleucotamine, (+/-)-narwedine, (-)-N-demethylgalanthamine, (+)-11-hydroxyvittatine, (+)-9-0-demethylhomolycorine, (-)-lycorine, (-)-galanthine, hordenine, and (E)-N-feruloyltyramine were also obtained. Of these alkaloids, only galanthamine and lycorine have been isolated previously from G. elwesii. Identification and structural elucidation were achieved using spectrometric techniques.

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