Two new (1and 2) and one known (3) sesquiterpene bis-butenolides have been isolated from the aerial parts of Eremophila homoplastica (Myoporaceae). The structures of the new compounds were determined by spectroscopic studies and confirmed by single-crystal X-ray crystallography of one (2) of the new compounds. Spectroscopic evidence for the structure of a new related sesquiterpene butenolide (4) from E. forrestii is presented. The isolation of the phenylethanoid glycosides, verbascoside and poliumoside, from E. forrestii is noted.