Catharanthus Alkaloids XXXVII. 16-Epi-Z-Isositsirikine, a Monomeric Indole Alkaloid with Antineoplastic Activity from Catharanthus roseus and Rhazya stricta

Journal of Natural Products
1983.0

Abstract

16-Epi-Z-isositsirikine (1) has been isolated from the leaves of Catharanthus roseus and Rhazya stricta and identified through a combination of spectral interpretation and chemical correlation. The compound displayed antineoplastic activity in the KB test system in vitro and the P-388 test system in vivo.

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