<jats:p> Nine alkaloids, including one new norsecurinine derivative norsecurinic acid (1), and two artificial alkaloid products, 15β-butoxy-14,15-dihydronorsecurinine (2) and 15α-butoxy-14,15-dihydronorsecurinine (3), were isolated from the root of Flueggea virosa. Their structures and configurations were elucidated by chemical and spectroscopic methods, especially 2D NMR techniques.