Chartrenoline, a novel alkaloid isolated from a marine Streptomyces chartreusis NA02069

Chinese Chemical Letters
2019.0

Abstract

A novel alkaloid, chartrenoline (1), featuring an unusual 6/6/5/5-tetracyclic nucleus, was isolated from a marine Streptomyces chartreusis NA02069. The structure of 1 including its absolute configurations was established by extensive analyses of its high resolution mass, NMR and single-crystal X-ray diffraction data. A plausible biosynthetic pathway for chartrenoline (1) is proposed.

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