Enhancement of the Diversity of Polyoxins by a Thymine-7-Hydroxylase Homolog outside the Polyoxin Biosynthesis Gene Cluster

Applied and Environmental Microbiology
2010.0

Abstract

<jats:title>ABSTRACT</jats:title> <jats:p> Polyoxins consist of 14 structurally variable components which differentiate at three branch sites of the carbon skeleton. Open reading frame (ORF) SAV_4805 of <jats:italic>Streptomyces avermitilis</jats:italic> , showing similarity to thymine-7-hydroxylase, was proved to enhance the diversity of polyoxins at the C-5 site of the 1-(5′-amino-5′-deoxy-β- <jats:sc>d</jats:sc> -allofuranuronosyl) pyrimidine moiety.

Knowledge Graph

Similar Paper

Enhancement of the Diversity of Polyoxins by a Thymine-7-Hydroxylase Homolog outside the Polyoxin Biosynthesis Gene Cluster
Applied and Environmental Microbiology 2010.0
Characterization of the Polyoxin Biosynthetic Gene Cluster from Streptomyces cacaoi and Engineered Production of Polyoxin H
Journal of Biological Chemistry 2009.0
Characterization of the Polyoxin Biosynthetic Gene Cluster from Streptomyces cacaoi and Engineered Production of Polyoxin H
Journal of Biological Chemistry 2009.0
Novel polyoxins generated by heterologously expressing polyoxin biosynthetic gene cluster in the sanN inactivated mutant of Streptomyces ansochromogenes
Microbial Cell Factories 2012.0
Cytochrome P450 complement (CYPome) of the avermectin-producer Streptomyces avermitilis and comparison to that of Streptomyces coelicolor A3(2)
Biochemical and Biophysical Research Communications 2003.0
SAV4189, a MarR-Family Regulator in Streptomyces avermitilis, Activates Avermectin Biosynthesis
Frontiers in Microbiology 2018.0
Characterization of a silent sesquiterpenoid biosynthetic pathway in <i>Streptomyces avermitilis</i> controlling <i>epi</i>‐isozizaene albaflavenone biosynthesis and isolation of a new oxidized <i>epi</i>‐isozizaene metabolite
Microbial Biotechnology 2011.0
Polyoxin N, a New Member of the Polyoxin Family
Agricultural and Biological Chemistry 1981.0
SdrA, a New DeoR Family Regulator Involved in Streptomyces avermitilis Morphological Development and Antibiotic Production
Applied and Environmental Microbiology 2013.0
Isolation and Characterization of New 16-Membered Macrolides from the <i>aveA3</i> Gene Replacement Mutant Strain <i>Streptomyces avermitilis</i> TM24 with Acaricidal and Nematicidal Activities
Journal of Agricultural and Food Chemistry 2019.0