Isolation of Apparicine from the Leaves of Ervatamia coronaria

Journal of Natural Products
1984.0

Abstract

Ervatamia coronaria Stapf (Apocynaceae) is a glabrous, evergreen tree that occurs abundantly in the gardens of West Pakistan. E. coronaria has found use in the indigenous system of medicine for the treatment of ophthalmia, for application on wounds and inflamed parts of the body, and as an anthelmintic. A number of alkaloids have been reported previously from the leaves, stem-bark, and roots of the plant (1-8). We have isolated an alkaloid that has been identified by spectroscopic studies as apparicine, mp 192- 194°, [α]D 177° (CHCl3), not previously reported from the leaves of this plant.

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