Taxodistines A and B, abietane-type diterpenes from Taxodium distichum

Bioorganic & Medicinal Chemistry Letters
2007.0

Abstract

Two new abietane-type diterpenes, taxodistines A (1) and B (2), have been isolated by the guidance of inhibitory effect of tubulin polymerization from the fruits of Taxodium distichum and the structures were elucidated by using 2D NMR data. Taxodistine B (2) showed inhibition of tubulin polymerization.

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