Literature

Abstract

Here we report the isolation of lolitrem A (4) from perennial ryegrass seed, its structure elucidation using mass spectrometry and one- and two-dimensional lH and 13C NMR techniques, and its tremorgenic activity in a standard mouse bioassay. We also report assignment of the proton and carbon resonances for the methyl groups of lolitrem B, completing the partial assignment reported by Gallagher et al. (1984) and thereby allowing the NMR spectral data for 1 and 4 to be reliably compared.

DOI： 10.1021/JF00053A029

Isolation and Structure Elucidation of Lolitrem A, a Tremorgenic Mycotoxin from Perennial Ryegrass Infected with Acremonium lolii

Journal of Agricultural and Food Chemistry 1995.0

Large-Scale Isolation of Lolitrem B and Structure Determination of Lolitrem E

Journal of Agricultural and Food Chemistry 1994.0

Lolitrems, peramine and paxilline: Mycotoxins of the ryegrass/endophyte interaction

Agriculture, Ecosystems & Environment 1993.0

Isolation of Lolicine A, Lolicine B, Lolitriol, and Lolitrem N from Lolium perenne Infected with Neotyphodium lolii and Evidence for the Natural Occurrence of 31-Epilolitrem N and 31-Epilolitrem F

Journal of Agricultural and Food Chemistry 1998.0

Terpendole M, a Novel Indole−Diterpenoid Isolated from Lolium perenne Infected with the Endophytic Fungus Neotyphodium lolii

Journal of Agricultural and Food Chemistry 1999.0

An Efficient Method for the Isolation of Peramine, an Insect Feeding Deterrent Produced by the Fungus Acremonium Lolii