In the course of our continuing study of the alkaloids from the roots of Thalictrumfaberi ULBR. (Ranunculaceae), a plant native to China used in folk medicine as an antiphlogistic and recently in the treatment of stomach cancer, we isolated three new aporphine-benzylisoquinoline dimers, (+)-thalifaberine (1), (+)-thalifabine (2), and (+)-huangshanine (3). (+)-Thalifaberine (1) and (+)-huangshanine (3) showed cytotoxicity against Walker 256 carcinoma cell. Structural elucidation using UV, mass spectrometry (EI, CI), NMR (including 60 MHz, 200 MHz, AA'BB' systems, tickling and double irradiation experiments), permanganate oxidation, Nuclear Overhauser Effect (NOE) difference spectroscopy, and circular dichroism (CD) revealed their structures: 1 and 2 are the first aporphine-benzylisoquinoline dimers with a 1,2,3,8,9,10-substituted aporphine moiety and a diphenyl ether linkage between C-8 of the aporphine and C-12' of the benzylisoquinoline moiety; 3 belongs to the fetidine class. CD analysis indicated an identical absolute configuration for all three dimers, similar to (+)-thalifaberine. (+)-Thalifaberine-type alkaloids differ from the (+)-thalicarpine, (+)-fetidine, and (+)-istanbulamine series in the positions of the ether bridge termini and the presence of an exceptional C-9-methoxyl group.