Alkaloids of Corydalis incisa PERS. III. The Structures of Corydamine Hydrochloride and N-Formyl Corydamine

Chemical and Pharmaceutical Bulletin
1973.0

Abstract

Two new alkaloids, corydamine hydrochloride, C20H19O4N2Cl, mp 235-239° (decomp.) and N-formyl corydamine, C21H18O4N2, mp 159.5-160.5°, were isolated from Corydalis incisa PERS. (Papaveraceae) and their structures were established to be II and IX, respectively, by spectroscopic analyses and their chemical conversion to coptisine iodide and anhydrodihydroprotopine-B. Corydamine hydrochloride and N-formyl corydamine are noted as the first naturally occurring alkaloids having the 3-phenyl isoquinoline skeleton.

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