The fruits of Iryanthera grandis contain the four compounds related with the tocotrienol group: 2,8 dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-6-chromanol; 2,8-dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl-5-0-[2',8'-dimethyl-2'-(4',8',12'-trimethyl-3',7',1 l'-tridecatrienyl)-6'chromanyl])d-chromanol; 2,8-dimethyl-2- (4,12-dimethyl-8-carboxy1-3,7,11-tridecatrienyl)-6-chromanol and 5-hydroxy-7-(3,7,1 l,lS-tetramethyl-2,6,10,1 l-hexadecatetraenyl-2(3H)-benzofuranone; the neolignan (2R,3R,4S)-2,3dimethyl-4-(4'-hydroxyphenyl)-6-hydroxytetralin; and the flavonoid 2',4'-dihydroxy-4,6'-dimethoxydihydrochalcone.