Identification of an unexpected shunt pathway product provides new insights into tirandamycin biosynthesis

Identification of an unexpected shunt pathway product provides new insights into tirandamycin biosynthesis Isolation and Characterization of Tirandamycins from a Marine-Derived <i>Streptomyces</i> sp. Isolation and Characterization of Tirandamycins from a Marine-Derived <i>Streptomyces</i> sp. Characterization of <i>TrdL</i> as a 10-Hydroxy Dehydrogenase and Generation of New Analogues from a Tirandamycin Biosynthetic Pathway Identification of 4,5-Dihydro-4-hydroxygeldanamycins As Shunt Products of Geldanamycin Biosynthesis Identification of 4,5-Dihydro-4-hydroxygeldanamycins As Shunt Products of Geldanamycin Biosynthesis Medium optimization of Streptomyces sp. 17944 for tirandamycin B production and isolation and structural elucidation of tirandamycins H, I and J Tirandalydigin, a novel tetramic acid of the tirandamycin-streptolydigin type. II. Isolation and structural characterization. Cytotoxic anthracycline and antibacterial tirandamycin analogues from a marine-derived Streptomyces sp. SCSIO 41399 Cytochrome P450 oxidase SlgO1 catalyzes the biotransformation of tirandamycin C to a new tirandamycin derivative