Literature

Abstract

Evidence is put forward which describes the structure and stereochemistry of new antibiotics, nanaomycins A and B, as I and V, respectively. In order to study biosynthesis and to determine the position of the hydroxyl group in the naphthoquinone moiety, a feeding experiment with 1-13C-acetate was effectively carried out. Nanaomycins A and B were found to be synthesized from acetate via a polyketide by Streptomyces rosa var. notoensis.

DOI： 10.7164/antibiotics.28.868

Nanaomycins, new antibiotics produced by a strain of Streptomyces. II. Structure and biosynthesis.

The Journal of Antibiotics 1975.0

Nanaomycins, new antibiotics produced by a strain of Streptomyces. I. Taxonomy, isolation, characterization and biological properties.

The Journal of Antibiotics 1975.0

Nanomycins, new antibiotics produced by a strain of Streptomyces. III. A new component, nanomycin C, and biological activities of nanaomycin derivatives.

The Journal of Antibiotics 1975.0

Bioconversion and biosynthesis of nanaomycins using cerulenin, a specific inhibitor of fatty acid and polyketide biosyntheses.

The Journal of Antibiotics 1980.0

OM-173,new nanaomycin-type antibiotics produced by a strain of streptomyces. Taxonomy,production,isolation and biological properties.

The Journal of Antibiotics 1983.0

Nanaomycin I and J: New nanaomycins generated by mycothiol-mediated compounds from “Streptomyces rosa subsp. notoensis” OS-3966